Current leakage from one cell depolarizes what?

Prepare for the Cardiac Electrophysiology Test. Study with flashcards and multiple choice questions, each question includes hints and explanations. Enhance your expertise and get ready for your certification!

Multiple Choice

Current leakage from one cell depolarizes what?

Explanation:
Electric current spreading from one cardiac cell to its neighbors through gap junctions causes those neighboring cells to depolarize. When this passively brought-nearby membrane potential reaches the threshold, voltage-gated channels activate and an action potential is generated in the next cell, propagating the impulse through the heart. This electrotonic spread explains how a single depolarization can trigger neighboring cells to fire without external synaptic input. It doesn’t primarily involve nerve endings, blood vessels, or the nucleus, which are not driven by this direct intercellular depolarizing current in the same way.

Electric current spreading from one cardiac cell to its neighbors through gap junctions causes those neighboring cells to depolarize. When this passively brought-nearby membrane potential reaches the threshold, voltage-gated channels activate and an action potential is generated in the next cell, propagating the impulse through the heart. This electrotonic spread explains how a single depolarization can trigger neighboring cells to fire without external synaptic input. It doesn’t primarily involve nerve endings, blood vessels, or the nucleus, which are not driven by this direct intercellular depolarizing current in the same way.

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